Elimination of a spiral wave pinned at an obstacle by a train of plane waves: Effect of diffusion between obstacles and surrounding media
M. Tanaka, M. Hörning, H. Kitahata* and K. Yoshikawa
Chaos, 25, 10, 2015, - doi : 10.1063/1.4934561
Brief Summary: ''... In this study, we investigated the difference in the unpinning of spiral waves from obstacles with and without diffusive interaction, and found a profound difference. The pacing period required for unpinning at fixed obstacle size is larger in case of diffusive obstacles. Further, we deduced a generic theoretical framework that can predict the minimal unpinning period. ...''
Excitable Signal Transduction Induces Both Spontaneous and Directional Cell Asymmetries in the Phosphatidylinositol Lipid Signaling System for Eukaryotic Chemotaxis
M. Nishikawa*, M. Hörning, M. Ueda and T. Shibata*
Biophysical Journal, 106, 3, 723-734, 2014 - doi : 10.1016/j.bpj.2013.12.023
Brief Summary: ''... Spatiotemporal dynamics of the phosphatidylinositol 3,4,5-trisphosphate (PIP3) is analyzed in Dictyostelium cells. It is shown that spontaneous activation of PIP3-enriched domains is generated by an intrinsic excitable system and how cells achieve high sensitivity to and robust coordination of the downstream activation that allows chemotactic behavior in the noisy environment. ...''