Mineralized scale patterns on the cell periphery of the chrysophyte Mallomonas determined by comparative 3D Cryo-FIB SEM data processing
M. Hörning, A. Schertel, R. Schneider, M.-L. Lemloh, M. R. Schweikert, and I. M. WeissJournal for Structural Biology
, 209, 107403, 2020
doi : 10.1016/j.jsb.2019.10.005
Brief Summary: ''... Computational automated routines and principal component analysis of the experimentally extracted Mallomonas data created a realistic mathematical model based on the Fibonacci pattern theory. A complete in silico scale case of Mallomonas was reconstructed showing an optimized scale coverage on the cell surface ...''
Three-dimensional cell geometry controls excitable membrane signaling in Dictyostelium cells
M. Hörning and T. ShibataBiophysical Journal
116(2), 372-382, 2019
doi : 10.1016/j.bpj.2018.12.012
Brief Summary: ''... Using a novel method of three-dimensional analysis of the entire cell membrane of Dictyostelium cells, we found that PtdInsP3 domains can propagate persistently in any direction on the entire plasma membrane, while their propagation direction and speed are governed by the geometry of the cell. ...''
Dynamics of spatiotemporal line defects and chaos control in complex excitable systems
M. Hörning, F. Blanchard, A. Isomura and K. Yoshikawa
Scientific Reports, 7, 7757, 2017
- doi : 10.1038/s41598-017-08011-z
Brief Summary: ''... We explore the spatiotemporal dynamics of line defects in rotating spiral waves. We combined a novel signaling over-sampling technique with a multi-dimensional Fourier analysis, showing that line defects can translate, merge, collapse and form stable singularities with even and odd parity while maintaining a stable oscillation of the spiral wave in the tissue. ...''
Dynamic Mechano-Regulation of Myoblast Cells on Supramolecular Hydrogels Cross-Linked by Reversible Host-Guest Interactions
M. Hörning§, M. Nakahata§, P. Linke, A. Yamamoto, M. Veschgini, S. Kaufmann, Y. Takashima, A. Harada and M. Tanaka
Scientific Reports, 7, 7760, 2017
- doi : 10.1038/s41598-017-07934-x
Brief Summary: ''... We apply a new class of reversible rigidity switching hydrogels to actively control cells. Actin depolarization dynamics as well as cellular responses are tracked over time. ...''